BioinformaticsbioRxivPreprint
OmniSyn unifies target-aware molecular generation and optimization within a synthesis-native LLM framework across the human proteome
Qin Zheng, Yuzhang Li, Yueqing Zhang…·Duanhua Cao
OmniSyn generates and optimizes target-specific molecules with synthesis traces using a sequence-conditioned LLM, achieving state-of-the-art performance on drug discovery benchmarks.
DOI 10.64898/2026.09.02.748775