Biswanath Chowdhury

The paper introduces ec3D, a method to reconstruct 3D structures of ecDNA from Hi-C data, revealing spherical configurations and unique long-range interactions in cancer.

The paper introduces OM2BFB, an algorithm detecting BFB amplifications using OGMs, showing high precision and recall, and finds BFB events are common in certain cancers but not linked to intratumoral heterogeneity or rapid genome change.

This paper introduces a genetic algorithm-based gene prediction method, GPGA, which improves efficiency by focusing on individual exons and demonstrates comparable performance on benchmark datasets and human chromosome 21 annotation.