Konrad Aden

This study shows that STING acts as a genome-integrity checkpoint in epithelial cells, independent of interferon, and its loss leads to chromosomal instability and tumor development.

This study identifies microbial-specific Trp metabolism signatures in colitis by analyzing metabolites across multiple compartments in mice treated with DSS and antibiotics.

The paper investigates gut microbiome changes in T3cDM patients, finding increased Escherichia-Shigella and reduced diversity, suggesting EPI drives microbial shifts rather than systemic metabolism.

This study identifies potential biomarkers for IBD diagnosis and monitoring through metaproteomics meta-analysis of over 600 samples.

This study uses metabolic modeling to uncover host-microbiome metabolic dysregulation in IBD, identifying key pathways and potential therapeutic interventions.

The paper examines the relationship between HK2 expression and inflammation severity in IBD patients using bulk transcriptome data and confirms findings at the cellular and protein levels.