NeuroscienceHuman Molecular GeneticsPeer-reviewed
High-fat diet-induced activation of SGK1 promotes Alzheimer's disease-associated tau pathology
Montasir Elahi, Yumiko Motoi, Shotaro Shimonaka…·Nobutaka Hattori
This study shows that high-fat diet-induced activation of SGK1 promotes tau pathology in Alzheimer's disease by phosphorylating tau and activating GSK-3β.