Author
University of ChicagoORCID 0000-0003-3500-5664Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Tolani F. Olonisakin, Fernando Tadeu Zamunér, Kenny Vu…·Nyall R. London
This study identifies molecular and immune mechanisms driving malignant transformation from inverted papilloma to sinonasal squamous cell carcinoma using multi-omics analyses.
Howell Leung, Chengchen Duan, Wenhao Gou…·Alex A. Zhavoronkov
This paper introduces a platform for disease-specific target identification using multi-omics data and evaluates models with a benchmarking system to improve drug development efficiency.
Weijie Guo, Daniel Leon, Jingyun Luan…·Yuxuan Miao
The paper identifies SOX2 as a master regulator of immune modulatory circuits in tumor-initiating stem cells, enabling immunosuppressive myeloid cell development.
Geoffrey Ho Duen Leung, Jianjiu Chen, I. Aylin Ergun…·Alex A. Zhavoronkov
The paper uses AI and causal genetics to identify shared therapeutic targets for aging and 12 age-related diseases across four disease areas.
Weijie Guo, Jingyun Luan, Xuejie Huang…·Yuxuan Miao
This study identifies tumor-initiating cells that modulate neutrophil plasticity to create a protective niche, preventing immunotherapy effectiveness.
Vladimir Naumov, Diana Zagirova, Sha Lin…·Alex A. Zhavoronkov
DORA AI Scientist automates scientific research tasks and report generation using multi-agent AI systems and LLMs, reducing manuscript preparation time and enabling more focus on discovery.
Genevieve Stein-O’Brien, Luciane Tsukamoto Kagohara, Sijia Li…·Elana Judith Fertig
The paper uses integrated time course omics analysis to distinguish immediate therapeutic response from acquired resistance in head and neck cancer.