Author

Jingyun Luan

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Yuxuan MiaoiD· 3 shared Alexander T. PearsoniD· 2 shared Ari Joseph RosenbergiD· 2 shared Benjamin NicholsoniD· 2 shared Daniel Leon· 2 shared Diana Bolotin· 2 shared Everett E. VokesiD· 2 shared Evgeny IzumchenkoiD· 2 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Yuxuan MiaoORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Integrated analysis of stemness-associated immune modulatory circuits in squamous cell carcinomas

Weijie Guo, Daniel Leon, Jingyun Luan, Audrey Gang, Xuejie Huang, Benjamin Nicholson, Karolina Dorosz, Yinhan Stacey Zhao, Sarra Grimshaw, Diana Bolotin, Mark William Lingen, Everett E. Vokes, Alexander T. Pearson, Ari Joseph Rosenberg, Le Shen, , Yuxuan Miao

The paper identifies SOX2 as a master regulator of immune modulatory circuits in tumor-initiating stem cells, enabling immunosuppressive myeloid cell development.

bioRxiv · Apr 6, 2026 · PreprintCancer Biology

Tumor-Initiating Cells Fine-tune the Plasticity of Neutrophils to Sculpt a Protective Niche

Weijie Guo, Jingyun Luan, Xuejie Huang, Daniel Leon, Sophie Gang, Benjamin Nicholson, Breanna Bertacchi, Diana Bolotin, Mark William Lingen, Alexander T. Pearson, Evgeny Izumchenko, Ari Joseph Rosenberg, Nishant Agrawal, Everett E. Vokes, Siwakorn Punyawatthananukool, , Yuxuan Miao

This study identifies tumor-initiating cells that modulate neutrophil plasticity to create a protective niche, preventing immunotherapy effectiveness.

Cancer Cell · Dec 4, 2025Peer-reviewedCancer Biology

SFyNCS detects oncogenic fusions involving non-coding sequences in cancer

Xiaoming Zhong, Jingyun Luan, Anqi Yu, Anna M. Lee-Hassett, Yuxuan Miao, Lixing Yang

SFyNCS detects oncogenic fusions involving non-coding sequences in cancer using transcriptomic data and validates them with genomic structural variations.

Nucleic Acids Research · Aug 28, 2023Peer-reviewedBioinformatics