Author

Ségolène Bernheim

InsermORCID 0000-0003-3506-6184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Audrey DesgrangeiD· 3 shared Sigolène M. MeilhaciD· 3 shared Jean‐François Le GarreciD· 2 shared Lucile HouyeliD· 2 shared Adrien BorgeliD· 1 shared Amaia Ochandorena-SaaiD· 1 shared Christophe ZimmeriD· 1 shared Damien BonnetiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersDevelopmental Biology

Audrey DesgrangeORCID

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3 papers

Recent·Most cited

Developmental BiologyCommunications BiologyPeer-reviewedDec 23, 2025

Deep learning-based detection of murine congenital heart defects from μCT scans

Hoa Nguyen, Audrey Desgrange, Amaia Ochandorena-Saa…·Christophe Zimmer

This paper develops deep learning models to automatically detect congenital heart defects in mouse CT scans, achieving high accuracy across different cohorts.

3 citations

mouseimaging

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMay 11, 2023

Torsion of the heart tube by shortage of progenitor cells : identification of Greb1l as a genetic determinant of criss-cross heart in mice

Ségolène Bernheim, Adrien Borgel, Jean‐François Le Garrec…·Sigolène M. Meilhac

The paper identifies Greb1l as a genetic determinant of criss-cross heart in mice by showing its role in maintaining precursor cells during heart tube elongation.

2 citations

mousestatistical model

𝕏 PostBluesky

Developmental BiologybioRxivPreprintNov 25, 2019

Transient Nodal signalling in left precursors coordinates opposed asymmetries shaping the heart loop

Audrey Desgrange, Jean‐François Le Garrec, Ségolène Bernheim…·Sigolène M. Meilhac

This study shows Nodal transiently coordinates left-right asymmetries in mouse heart development through a heart-specific random generator, amplifying asymmetry to generate a robust helical shape.

2 citations

mousestatistical model

𝕏 PostBluesky