Author

Claire Leloup

Institut PasteurORCID 0000-0003-3525-0854Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Lars RoggeiD· 2 shared Ambre Dangien· 1 shared Ana Esteve‐SoléiD· 1 shared Andrés Augusto AriasiD· 1 shared Andrés BaenaiD· 1 shared Aniss RafikiD· 1 shared Anne M. FourieiD· 1 shared Anne PueliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Lars RoggeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GeneticsThe Journal of Experimental MedicinePeer-reviewedJul 9, 2026

✦ In-depth digest

Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis

Diana Olguín-Calderón, Laura E. Kilpatrick, Clément Conil…·Stéphanie Boisson‐Dupuis

Homozygosity for hypomorphic IL23R variants (G149R, G300V, R381Q) partly impairs IL-23-dependent IFN-γ production in patient cells; with L372F (effect inferred), they are enriched in tuberculosis, not MSMD or CMC patients.

1 citation

humanwhole-exome sequencing

𝕏 PostBluesky

ImmunologyiSciencePeer-reviewedJan 25, 2025

IL-23 tunes inflammatory functions of human mucosal-associated invariant T (MAIT) cells

Laetitia Camard, Tharshana Stephen, Hanane Yahia‐Cherbal…·Lars Rogge

This study identifies IL-23's role in shaping the functional plasticity of human MAIT cells, revealing its impact on autoimmunity and cytotoxic functions through AP-1 transcription factors.

12 citations

humanbulk RNA-seq

𝕏 PostBluesky