IL-23 tunes inflammatory functions of human mucosal-associated invariant T (MAIT) cells
Laetitia Camard, Tharshana Stephen, Hanane Yahia‐Cherbal, Vincent Guillemot, Sébastien Mella, Victoire Baillet, Hélène Lopez-Maestre, Daniele Capocefalo, Laura Cantini, Claire Leloup, Julie Marsande, Katherine Garro, Juan Sienes Bailo, Ambre Dangien, Natalia Pietrosemoli, , Lars Rogge
This study identifies IL-23's role in shaping the functional plasticity of human MAIT cells, revealing its impact on autoimmunity and cytotoxic functions through AP-1 transcription factors.
iScience · Jan 25, 2025Peer-reviewedImmunology