Honghai Zhang

This study identifies GPR30 in spinal CCK+ neurons and S1-SDH postsynaptic neurons as critical for neuropathic pain, suggesting it as a therapeutic target.

This study investigates how sevoflurane anesthesia affects consciousness by examining the role of locus coeruleus to medial prefrontal cortex noradrenergic circuits in mice.

This study identifies the role of the LC-VLPO noradrenergic circuit and GABAA-R in midazolam-induced unconsciousness and its recovery.

This study shows curcumin reduces neuropathic pain by inhibiting the Cdk5/p35 signaling pathway in microglia, affecting neuronal plasticity and synaptic remodeling.

The paper investigates the synergistic role of central serotonergic and noradrenergic circuits in modulating SUDEP through experimental methods and identifies a potential therapeutic target.

This study identifies a serotonergic pathway between the central amygdala and medial prefrontal cortex that accelerates sevoflurane anesthesia recovery, particularly in individuals with anxiety and depression.

The study investigates the role of 5-HT neurons and their receptors in mediating delayed awakening from sevoflurane anesthesia in mice.

This study investigates the role of noradrenergic neurons in the locus coeruleus and β1-AR in cardiomyocytes in modulating SUDEP through respiratory and cardiac arrhythmias.

The paper investigates how norepinephrine synthesis and neurotransmission deficits contribute to seizure-induced respiratory arrest and identifies NE-1R as a potential therapeutic target for SUDEP prevention.

The paper investigates the role of the VGLUT2/Cdk5/p25 signaling pathway in inflammatory pain induced by CFA and shows that roscovitine inhibits this pathway.