NeuroscienceNeurophotonicsPeer-reviewed
Desensitization of opsin responses during all-optical interrogation depends on imaging parameters
Blake Russell, Robert M. Lees, Armin Lak, Adam M. Packer
This study shows that two-photon imaging at 920 nm during optogenetic stimulation increases opsin desensitization in C1V1-expressing neurons, affecting both targeted and non-targeted cells.