Robert M. Lees

This study shows that low-dose synchrotron CT can image bovine intervertebral discs repeatedly without damaging their mechanical, microstructural, or molecular properties.

This study shows that two-photon imaging at 920 nm during optogenetic stimulation increases opsin desensitization in C1V1-expressing neurons, affecting both targeted and non-targeted cells.

The paper identifies a unique pericystic endothelium in ADPKD that contributes to microvascular remodelling and impaired perfusion, suggesting vascular targets for early intervention.

The paper introduces a test to assess the relevance of trial-averaged neuronal metrics to neuronal computation, finding they are less relevant in less controlled settings.

This protocol provides standardised measurements to assess and compare multiphoton microscope performance across users.

This paper investigates the factors affecting spatial precision in two-photon optogenetic photostimulation and finds that optical resolution is not the limiting factor.

The paper investigates how neural variability in the somatosensory cortex affects the perception and propagation of activity between brain regions in mice.

The paper investigates how mitochondrial positioning affects the stability of presynaptic boutons in mouse neocortex, finding that mitochondrial localization correlates with increased bouton stability over time.