Cancer BiologybioRxivPreprint
An immunocompetent osteoblastic model of mammary cancer bone metastasis established by syngeneic intratibial injection of PyMT mammary carcinoma cells in FVB/N mice
Courtney L. Flatt, Sarah Nano, Ria Goyal…·Laurie E. Littlepage
This paper develops an immunocompetent mouse model of osteoblastic breast cancer bone metastasis using PyMT-CK(OB) cells and validates its utility for studying immune-dependent bone remodeling mechanisms.
DOI 10.64898/2026.07.08.737245