Author

Bora Lim

Baylor College of MedicineORCID 0000-0002-4182-6058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

Emi SeiiD· 2 shared Hui CheniD· 2 shared Nicholas E. NaviniD· 2 shared Scott KopetziD· 2 shared Shanshan BaiiD· 2 shared Tod D. CasasentiD· 2 shared Aatish ThennavaniD· 1 shared Aislyn P. SchalckiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Emi SeiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness

Elena Oropeza, Sinem Şeker, Sabrina Carrel, Aloran Mazumder, Daniel Lozano, Athena Jimenez, Sabrina N. VandenHeuvel, Dillon A. Noltensmeyer, Nindo B. Punturi, Jonathan Thomas Lei, Bora Lim, Susan E. Waltz, Shreya A. Raghavan, Matthew Neil Bainbridge, Svasti Haricharan

This study identifies how specific cell cycle checkpoint kinase dysregulations influence cancer subtype, metastasis, and treatment response in breast cancer.

Science Advances · Jun 30, 2023Peer-reviewedCancer Biology

A spatially resolved single cell genomic atlas of the adult human breast

Tapsi Kumar, Kevin Nee, Runmin Wei, Siyuan He, Quy Nguyen, Shanshan Bai, Kerrigan Blake, Maren Pein, Yanwen Gong, Emi Sei, Min Shan Hu, Tod D. Casasent, Aatish Thennavan, Jianzhuo Li, Tuan Tran, , Nicholas E. Navin

This paper constructs a comprehensive spatially resolved single-cell genomic atlas of the adult human breast, identifying 11 major cell types and revealing diverse immune and epithelial cell populations.

Nature · Jun 28, 2023Peer-reviewedGenomics

Resolving clonal substructure from single cell genomic data using CopyKit

Darlan Conterno Minussi, Emi Sei, Junke Wang, Aislyn P. Schalck, Yun Yan, Alexander Davis, Hua‐Jun Wu, Shanshan Bai, Cheng Peng, Min Hu, Tod D. Casasent, Alejandro Contreras, Hui Chen, David Hui, Senthil Damodaran, , Nicholas E. Navin

CopyKit is a computational tool that resolves clonal substructure and reconstructs genetic lineages in tumors using single cell copy number data.

bioRxiv · Mar 9, 2022 · PreprintGenomics

Tumor cell total mRNA expression shapes the molecular and clinical phenotype of cancer

Shaolong Cao, Jennifer Rui Wang, Shuangxi Ji, Yang Peng, Matthew D. Montierth, Shuai Guo, John Paul Shen, Xiao Ling Zhao, Jingxiao Chen, Jaewon James Lee, Paola A. Guerrero, Nicholas Spetsieris, Nikolai Engedal, Sinja Taavitsainen, Kaixian Yu, , Wenyi Wang

The paper quantifies tumor-specific total mRNA expression from bulk data and shows its association with clinical outcomes across 15 cancer types.

bioRxiv · Sep 30, 2020 · PreprintGenomics