Kevin Verstaen

The paper develops a method to select optimal TCR transgenic clones using single-cell RNA sequencing and TCR repertoire analysis, enabling the generation of CORSET8 mice specific to SARS-CoV-2 Spike protein.

This study compares antibody- and lipid-based hashing methods for single-cell RNA-seq, finding antibody-based hashing more efficient and cost-effective for clinical samples.

DALI is a software tool that integrates multimodal single-cell RNA-seq and immune receptor data to analyze T and B cell diversity, supporting both bioinformaticians and immunologists.