Kyong Soo Park

This paper conducts a multi-ancestry time-to-event GWAS to identify genetic variants associated with incident cardiovascular disease in people with type 2 diabetes, finding three novel loci and confirming known CAD variants.

The paper evaluates penetrance and variable expressivity of monogenic metabolic conditions using exome data from 77,184 individuals, finding that monogenic variants have larger effect sizes than polygenic scores but low penetrance.

This paper identifies 56 new type 2 diabetes loci in 433,540 East Asian individuals through a meta-analysis of GWAS data.

This study identifies ROCK1 as a mediator of melanocortin's anorexigenic effect through a novel signaling pathway involving G12 and AMPK suppression.

The paper examines the functional differences of mitochondrial genomes in metabolic syndrome and cancer using cybrid cells, finding associations with disease traits and tumorigenicity.

This paper develops a method integrating family history with genetic data to improve type 2 diabetes risk prediction, showing family history adds significant predictive value beyond genetic variants.