Author

Stephen David Hursting

University of North Carolina at Chapel HillORCID 0000-0003-3605-2833Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Michael F. ColemaniD· 3 shared Elaine M. GlennyiD· 2 shared Adetunji T. ToriolaiD· 1 shared Aik Choon TaniD· 1 shared Alessandro Carpanese· 1 shared Alexander BrobeiliD· 1 shared Alyssa N. HoiD· 1 shared Annie Green HowardiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersCancer Biology

Michael F. ColemanORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cancer Biologynpj Breast CancerPeer-reviewedSep 29, 2026

Obesity Impairs the Antitumor Activity of CAR-T Cells in Triple-Negative Breast Cancer

Hannah M. Malian, Caroline Marnata, Hannah M. Oh…·Michael F. Coleman

This study shows obesity impairs B7-H3.CAR-T cell antitumor activity and memory formation in TNBC by altering cytokine profiles and metabolic function.

2 citationstop 3%

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintFeb 10, 2026

Obesity and Tumor Development Reprogram the Proteome and Metabolic Effects of Adipose- and Tumor-Derived Extracellular Vesicles

Emma J. Grindstaff, Laith A. Rayyan, Yazan Alwarawrah…·Ximena Minerva Bustamante-Marin

This study examines how obesity and tumor progression alter the proteomic composition and metabolic effects of extracellular vesicles from adipose tissue and tumors.

DOI 10.64898/2026.02.08.704727

mouseproteomics

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PhysiologybioRxivPreprintJul 18, 2025

Urinary Signatures Predict Calorie Restriction-Mediated Weight Loss in Obese Diversity Outbred Mice

Evan M. Paules, Isis Trujillo‐Gonzalez, Melissa VerHague…·Stephen David Hursting

The paper identifies urinary metabolite signatures predictive of calorie restriction-mediated weight loss in obese mice, with sex-specific differences observed.

1 citation

mousemetabolomics

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Cancer BiologybioRxivPreprintJun 19, 2025

Obesity promotes conserved inflammatory and metabolic transcriptional programs in mouse and human colon tumors

Elaine M. Glenny, Tengda Lin, Victoria Maria Bandera…·Stephen David Hursting

This study identifies obesity-driven inflammatory and metabolic transcriptomic signatures in mouse and human colon tumors through integrated transcriptomic analyses.

DOI 10.1101/2025.06.19.660576

mousehuman

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