Alexander Brobeil

Spatialproteomics - an interoperable toolbox for analyzing highly multiplexed fluorescence image data

The paper introduces spatialproteomics, a Python toolbox for analyzing highly multiplexed fluorescence images, demonstrating its use on lymph node and lymphoma data.

Metabolic specialization structures gut bacterial niches and drives colorectal cancer progression

This study identifies Leptotrichia wadei as a pro-tumorigenic bacterium in CRC by linking metabolic specialization to microbial niches and tumor progression.

Obesity promotes conserved inflammatory and metabolic transcriptional programs in mouse and human colon tumors

This study identifies obesity-driven inflammatory and metabolic transcriptomic signatures in mouse and human colon tumors through integrated transcriptomic analyses.