Author

Ellie Guardino

GenentechORCID 0000-0003-3617-5788Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:electronic health records· 1 Research Focus:GWAS / association mapping· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Amy Pickar Abernethy· 1 shared Antonia KwaniD· 1 shared Bryan E. Bowser· 1 shared Che‐hsu Chang· 1 shared Christian HammeriD· 1 shared Deb Schrag· 1 shared Flavia Di Nucci· 1 shared G. Scott ChandleriD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Amy Pickar Abernethy

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2 papers

Recent·Most cited

GeneticsProceedings of the National Academy of SciencesPeer-reviewedMay 19, 2020

Polygenic Risk for Skin Autoimmunity Impacts Immune Checkpoint Blockade in Bladder Cancer

Zia Khan, Flavia Di Nucci, Antonia Kwan…·Matthew L. Albert

The paper shows that polygenic risk scores for skin autoimmunity affect the response to immune checkpoint blockade in bladder cancer, with higher vitiligo and psoriasis scores linked to better outcomes.

91 citationstop 3%

humanwhole-genome sequencing

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BioinformaticsAdvances in TherapyPeer-reviewedMay 28, 2019

Generating real-world tumor burden endpoints from electronic health record data: Comparison of RECIST, radiology-anchored, and clinician-anchored approaches for abstracting real-world progression in non-small cell lung cancer

Sandra D. Griffith, Melisa Tucker, Bryan E. Bowser…·Amy Pickar Abernethy

This study compares methods for extracting real-world progression data from EHRs in NSCLC, finding that clinician-anchored approaches with radiology support are most effective.

159 citationstop 1%

humanelectronic health records

𝕏 PostBluesky