Author

Lucía Graña-Miraglia

University of TorontoORCID 0000-0003-3626-4537Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

David S. GuttmaniD· 2 shared Alireza EshaghiiD· 1 shared Cedoljub Bundalovic-TormaiD· 1 shared David M. HwangiD· 1 shared Helen Elizabeth GrovesiD· 1 shared Jahir M. GutierreziD· 1 shared Jonathan B. GubbayiD· 1 shared Marc R. Isabel· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenomics

David S. GuttmanORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 25, 2022

Predictive modeling of antibiotic eradication therapy success for new-onset Pseudomonas aeruginosa pulmonary infections in children with cystic fibrosis

Lucía Graña-Miraglia, Nadia P. Morales-Lizcano, Pauline W. Wang…·David S. Guttman

The paper uses machine learning to predict antibiotic eradication therapy success for Pseudomonas aeruginosa infections in cystic fibrosis patients based on genomic data, achieving an AUC of 0.87.

DOI 10.1101/2022.10.25.513740

humanDNA methylation

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BioinformaticsScientific ReportsPeer-reviewedAug 20, 2020

Evolutionary and structural analyses of SARS-CoV-2 D614G spike protein mutation now documented worldwide

Sandra Isabel, Lucía Graña-Miraglia, Jahir M. Gutierrez…·Susan Marie Poutanen

The paper analyzes the global spread and structural impact of the D614G mutation in the SARS-CoV-2 spike protein, finding it predominant in Europe and neutral in function regarding ACE2 receptor binding.

200 citationstop 3%

viruswhole-genome sequencing

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