Vanessa Judith Flegler

The paper presents the high-resolution structure of Escherichia coli MscL in nanodiscs, revealing a pentameric assembly and a previously unreported dimeric association.

The paper investigates the structural gating mechanisms of YnaI, showing it opens via radial relocation of sensor paddles and pore shortening, contrasting with MscS's tilt-based mechanism.

This paper determines the structure of lymphostatin, a multifunctional virulence factor in E. coli, revealing its domains and mechanism of action.