Author

Christian Kraft

University of WürzburgORCID 0000-0002-6483-4296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Assay:protein structure· 2 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

Bettina BöttcheriD· 3 shared Tim RasmusseniD· 2 shared Vanessa Judith FlegleriD· 2 shared Akiko RasmusseniD· 1 shared Allison Ballandras-ColasiD· 1 shared Aurélia C. BalestraiD· 1 shared Clemens GrimmiD· 1 shared Frédéric IseniiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Bettina BöttcherORCID

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3 papers

Recent·Most cited

The Structure of Escherichia coli MscL and its dimer formation in Nanodiscs

Tim Rasmussen, Julia Isabel Bahner, Vanessa Judith Flegler, Tamsanqa Tafara Hove, Christian Kraft, Akiko Rasmussen, Bettina Böttcher

The paper presents the high-resolution structure of Escherichia coli MscL in nanodiscs, revealing a pentameric assembly and a previously unreported dimeric association.

Journal of Molecular Biology · Aug 4, 2026Peer-reviewedMolecular Biology

Lymphostatin: Structure of a large multi-functional virulence factor

Matthias Grießmann, Tim Rasmussen, Vanessa Judith Flegler, Christian Kraft, Ronja Schneider, Max Hateley, Lukas Spantzel, Mark P. Stevens, Michael Börsch, Bettina Böttcher

This paper determines the structure of lymphostatin, a multifunctional virulence factor in E. coli, revealing its domains and mechanism of action.

Nature Communications · Jun 25, 2025Peer-reviewedBiophysics

Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus

Wim Pascal Burmeister, Laetitia Boutin, Aurélia C. Balestra, Henri Gröger, Allison Ballandras-Colas, Stephanie Hutin, Christian Kraft, Clemens Grimm, Bettina Böttcher, Utz Fischer, Nicolas Tarbouriech, Frédéric Iseni

The paper presents the 3.8 Å cryo-EM structure of the VACV DNA polymerase holoenzyme and shows its structural similarity to MPXV, with transient E9-D4 interactions and conformational flexibility.

PLoS Pathogens · May 20, 2024Peer-reviewedMolecular Biology