Developmental BiologyPLoS BiologyPeer-reviewed
Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids.
Sapna Chhabra, Lizhong Liu, Ryan Goh…·Aryeh Warmflash
The paper shows BMP signaling initiates WNT, which initiates NODAL in human gastruloids, revealing dynamic signaling waves that mediate epiblast patterning without a signaling gradient.
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