Maria-Vittoria Mazzuoli

This study identifies Mnh1 as a key cation/proton antiporter promoting S. aureus phagocytic uptake and intracellular survival in human monocytes, suggesting it as a therapeutic target.

The paper uses CRISPRi-Seq to identify conserved antibiotic vulnerabilities in S. aureus strains, revealing gene targets for antimicrobial therapies.

This study shows that CovR, a virulence regulator, enhances CRISPR-Cas9 immunity in Group B Streptococcus by modulating Cas9 activity and improving immune memory.

This paper develops mbPE, a prime editing system for Streptococcus pneumoniae that enables precise genome editing without donor DNA, achieving high selection efficiencies for point mutations, deletions, and insertions.

This study investigates the role of HU in chromosome organization and replication in Streptococcus pneumoniae, showing it promotes long-range interactions and supports replication and segregation.

This study identifies two-component regulatory networks in Streptococcus agalactiae by activating histidine kinases to reveal connections between regulatory systems and their roles in pathogenicity and cell envelope homeostasis.