Molecular BiologybioRxivPreprint
Bypass of Blocking Lesions by RNAPII Impairs the Transcriptional DNA Damage Response
Carolina P. Bañuelos, Lucas D. Caeiro, Pradeep Reddy Cingaram…·Ramiro E. Verdún
The paper shows that RNAPII bypassing DNA lesions, regulated by p300, leads to genome instability and reduced cell proliferation.
DOI 10.1101/2025.04.28.651040