Cynthia L. Smith

This paper introduces a genomic framework to prioritize mouse strains for preclinical disease modeling, showing high sensitivity in predicting strain vulnerability to diseases.

The paper updates the Alliance of Genome Resources' central infrastructure, adding tools and enhancing data management and curation capabilities.

The paper converts human GO-CAMs to mouse GO-CAMs to link gene pathway perturbations with phenotypes, showing distinct outcomes from glycolysis and gluconeogenesis gene mutations.

This paper investigates the functional roles of mutable linker regions in HIV-1 Rev by testing truncation and substitution mutations, revealing their impact on protein stability and function.