Author
University of California, San FranciscoORCID 0000-0002-2525-9508Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Amber M. Smith, Yang Li, Arianna Velarde, Yifan Cheng, Alan D. Frankel
The paper determines the cryo-EM structure of the HIV-1 nuclear export complex, revealing how RNA interacts with Crm1 through specific binding sites and contacts.
Molecular Cell · Aug 1, 2025Peer-reviewedBiochemistry
David Ezra Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Hüttenhain, Robyn M. Kaake, Alicia Richards, Beril Tutuncuoglu, , Natalia Jura
Affinity-purification mass spectrometry of 26 SARS-CoV-2 proteins in HEK293T cells yields 332 high-confidence host interactions and 67 druggable human proteins with known compounds.
Nature · Apr 30, 2020Peer-reviewedSystems Biology✦ In-depth digest
Bhargavi Jayaraman, Jason D. Fernandes, Shumin Yang, Cynthia L. Smith, Alan D. Frankel
This paper investigates the functional roles of mutable linker regions in HIV-1 Rev by testing truncation and substitution mutations, revealing their impact on protein stability and function.
Scientific Reports · Mar 26, 2019Peer-reviewedMolecular Biology