Frédéric Lesage

The paper uses simulations to show brain microvascular networks provide oxygen supply resilience against hypoxia by maintaining oxygen tension through convective transport and capillary flow patterns.

This paper simulates MRI signatures of microstrokes using ASL and DWI, showing significant signal changes with ASL after photothrombosis.

This paper develops a deep learning method for segmenting brain vasculature from two-photon microscopy images, achieving faster computation and better generalization across imaging systems.

The paper measures capillary flow and oxygenation in cortical layers of awake mice, finding homogenization of oxygen delivery and increased extraction in layer IV.