Author

Paul A.M. Michels

University of EdinburghORCID 0000-0003-3726-6104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Aline Rimoldi· 1 shared Aysima HacisuleymaniD· 1 shared Corinne AsencioiD· 1 shared D.K. InaokaiD· 1 shared Edern CahoreauiD· 1 shared Emmanuel TétaudiD· 1 shared Erika PinedaiD· 1 shared Frédéric BringaudiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Aline Rimoldi

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2 papers

Recent·Most cited

MicrobiologyPLoS BiologyPeer-reviewedMay 16, 2025

The glycosomal ATP-dependent phosphofructokinase of Trypanosoma brucei operates in the gluconeogenic direction in cellulo under in vivo-like conditions

Nicolas Plazolles, Hanna Kulyk, Edern Cahoreau…·Frédéric Bringaud

This paper shows that ATP-dependent phosphofructokinase (PFK) in Trypanosoma brucei functions gluconeogenically in vivo, challenging its traditional role in glycolysis.

2 citations

humanexperimental assay

𝕏 PostBluesky

BiochemistryeLifePeer-reviewedAug 21, 2024

Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody

Joar Esteban Pinto Torres, Mathieu Claes, Rik Hendrickx…·Yann G.‐J. Sterckx

This study identifies a camelid single-domain antibody that allosterically inhibits trypanosomatid pyruvate kinases, reducing parasite growth.

6 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky