Francesco Asnicar

The paper identifies distinct microbiome and metabolomic signatures in treatment-naive multiple sclerosis patients compared to healthy controls across multiple biofluids.

LAMPP provides a standardized benchmark for evaluating host phenotype prediction from gut metagenomic data, showing that traditional methods remain competitive.

The paper evaluates metagenomic analysis methods in simulated and real environmental data, finding that newer marker-based methods perform better at lower taxonomic levels.

The paper presents a method to discover new human gut viruses using enriched virome samples and reports over 162,000 novel viral sequences.

Marker genes for 26,970 species-level genome bins, 4,992 defined only by metagenome-assembled genomes, let MetaPhlAn 4 quantify uncharacterized species and beat MetaPhlAn 3, mOTUs and Bracken on synthetic benchmarks.