Nadja Nolte

LongPolyASE: An end-to-end framework for allele-specific gene and isoform analysis in polyploids using long-read RNA-seq

The paper introduces LongPolyASE, a framework for allele-specific gene and isoform analysis in polyploids using long-read RNA-seq, demonstrating its application on rice and potato.

The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance

The paper demonstrates that long-read RNA-seq with quality control measures reduces bias in allele counts across four species, improving accuracy in allelic imbalance studies.

Multiparent Recombinant Inbred lines crossed to a tester provide novel insights into sources of cis and trans regulation of gene expression

The paper introduces a method using multi-parent RILs crossed to a tester to dissect cis and trans regulation of gene expression in Drosophila, finding environmental and genetic trans effects in 31% and 19% of loci respectively.

CATD: A reproducible pipeline for selecting cell-type deconvolution methods across tissues

This paper evaluates 31 cell-type deconvolution methods across human and mouse tissues, identifies regression-based methods as effective, and introduces the CATD pipeline for reproducible analysis.