Jonathan Lopez

This study compares immune gene expression in ICU and non-ICU Legionnaires' disease patients after LPS stimulation, finding more pronounced functional impairments in ICU patients.

This study maps spatial tumour-immune interactions in melanoma and identifies how their organization affects anti-PD1 therapy efficacy.

This study examines the spatial organization of dendritic cell (DC) subsets and their interactions with CD8+ T cells in melanoma patients, finding that proximity between cDC1 and CD8+ T cells correlates with response to immune checkpoint inhibitors.

The paper identifies critical sequencing parameters for reliable detection of expression changes, fusions, and variants in targeted RNA sequencing of tumor samples.