Christophe Caux

The paper examines the spatial organization of dendritic cell subsets in NSCLC patients treated with anti-PD1 and finds that cDC1-driven patterns correlate with prolonged ICB response.

IntegrAlign integrates multiimmunofluorescence panels through image alignment, achieving sub-cellular precision and improving spatial analysis of tumor microenvironments.

This study maps spatial tumour-immune interactions in melanoma and identifies how their organization affects anti-PD1 therapy efficacy.

The paper shows reduced TLR9 expression in breast cancer cells and links it to decreased proliferation and activation of senescence-related factors.

This study identifies neutrophils as the earliest immune cells involved in surveilling preneoplastic breast cancer cells through UPR activation and immunogenic signaling.

This study examines the spatial organization of dendritic cell (DC) subsets and their interactions with CD8+ T cells in melanoma patients, finding that proximity between cDC1 and CD8+ T cells correlates with response to immune checkpoint inhibitors.