Macy E. Zardeneta

The paper evaluates the long-term effects of miR-20a-3p treatment on brain pathology in female rats after ischemic stroke, finding reduced white matter volume and microglial activation in untreated animals.

The paper identifies lipid droplet-accumulating microglia (LAM) as a dysfunctional, pro-inflammatory state in aging brains, linked to neurodegeneration.

The paper analyzes aging dynamics across 17 organs and plasma proteomics in mice, revealing consistent gene expression trajectories with organ-specific timing and amplitude.

The paper creates a single-cell transcriptomic atlas of 20 mouse organs and tissues, providing a resource for studying gene expression across cell types.