Author

Maria Marta Garcia Alai

European Molecular Biology LaboratoryORCID 0000-0003-3788-3399Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

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Florian VogeleiD· 1 shared Francisca PinheiroiD· 1 shared Iara Plácido Guazzelli· 1 shared Jan Stanislaw NowakiD· 1 shared Magnus KjærgaardiD· 1 shared Osvaldo BurasteroiD· 1 shared Vili LampineniD· 1 shared

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2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Florian VogeleORCID

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1 paper

Recent·Most cited

BiophysicsProtein SciencePeer-reviewedSep 30, 2026

Global analysis of thermal and chemical denaturation using CheMelt: Thermodynamic dissection of highly thermostable de novo designed proteins

Vili Lampinen, Osvaldo Burastero, Iara Plácido Guazzelli…·Magnus Kjærgaard

The paper introduces CheMelt, a tool for analyzing thermal and chemical denaturation of proteins, and shows de novo designed proteins have lower thermodynamic parameters than natural proteins.

DOI 10.1002/pro.70800

protein structuredeep learning

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