BiophysicsProtein SciencePeer-reviewed
Global analysis of thermal and chemical denaturation using CheMelt: Thermodynamic dissection of highly thermostable de novo designed proteins
Vili Lampinen, Osvaldo Burastero, Iara Plácido Guazzelli…·Magnus Kjærgaard
The paper introduces CheMelt, a tool for analyzing thermal and chemical denaturation of proteins, and shows de novo designed proteins have lower thermodynamic parameters than natural proteins.
DOI 10.1002/pro.70800