Author

Maria Anna Kowalska

Children's Hospital of PhiladelphiaORCID 0000-0003-3849-8812Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Douglas B. CinesiD· 2 shared Khalil H. BdeiriD· 2 shared Mortimer PoncziD· 2 shared Amrita SarkariD· 1 shared Conroy O. FieldiD· 1 shared Gowthami M. ArepallyiD· 1 shared Guohua Zhou· 1 shared Hyun-Sook Ahn· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Douglas B. CinesORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 7, 2025

Antiphospholipid syndrome (APS) is a platelet factor 4 (PF4)-centric immunothrombotic disorder

Conroy O. Field, Amrita Sarkar, Khalil H. Bdeir…·Mortimer Poncz

This study identifies PF4 as a central factor in APS by showing it bridges {beta}2GPI to NETs, forming prothrombotic complexes that are targeted by APS antibodies.

2 citations

mouseexperimental assay

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Cell BiologybioRxivPreprintDec 5, 2023

Packaging of supplemented urokinase into naked alpha-granules of in vitro-grown megakaryocytes for targeted therapeutic delivery

Mortimer Poncz, Sergei V Zaitsev, Hyun-Sook Ahn…·Victoria V. Stepanova

The paper demonstrates that in vitro-grown megakaryocytes can store exogenous uPA in alpha-granules, which can be used to generate anti-thrombotic human platelets that lyse nascent thrombi in a mouse model.

DOI 10.1101/2023.12.05.570278

mouseproteomics

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