Author
Andreas Lange
University of MünsterORCID 0000-0003-3871-1986Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 13 mutual co-author links5 papers
Recent·Most cited
- GeneticsMolecular Biology and EvolutionPeer-reviewed
Orthologs of an essential orphan gene vary in their capacities for function and subcellular localization in Drosophila melanogaster
Prajal H. Patel, Lars A. Eicholt, Andreas Lange…·Geoffrey D. Findlay
The paper investigates functional and localization differences among orthologs of the Drosophila melanogaster essential gene gdrd, finding that some orthologs can rescue fertility while others cannot due to structural and physicochemical differences.
2 citationstop 2% - Evolutionary BiologyThe AnalystPeer-reviewed
Studying the evolutionary potential of ancestral aryl sulfatases in the alkaline phosphatase family with droplet microfluidics
Bernard D. G. Eenink, Josephin Marie Holstein, Magdalena Heberlein…·Andreas Lange
The paper uses droplet microfluidics to study the evolvability and robustness of ancestral and extant aryl sulfatases under varying mutation rates.
- BiochemistrybioRxivPreprint
Structure-function analysis of Factor Seven Activating Protease (FSAP) by in-silico methods and its expression in insect cells.
Sai Priya Sarma Kandanur, Abdulbaki Çoban, Andreas Lange…·Sandip M. Kanse
This study expresses FSAP in insect cells, analyzes its structure using AlphaFold and molecular dynamics, and identifies key interactions involved in its activation.
DOI 10.1101/2025.01.07.631702 - Molecular BiologyProtein SciencePeer-reviewed
Chaperones facilitate heterologous expression of naturally evolved putative de novo proteins
Lars A. Eicholt, Margaux Aubel, Katrin Berk…·Andreas Lange
This study improves the expression of de novo proteins in E. coli by using chaperones and specific expression systems, increasing solubility from 30% to 62%.
18 citations