Systems BiologyPLoS Computational BiologyPeer-reviewed
Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity
Szilvia Barsi, Henrietta Papp, Alberto Valdeolivas…·Bence Szalai
The paper identifies plasma membrane cholesterol depletion as a key mechanism of antiviral drug activity against SARS-CoV-2 through gene expression analysis and functional experiments.
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