Balázs Papp

The paper detects stabilizing selection on human plasma proteins by integrating genetic and fitness-related evidence across multiple approaches.

The paper develops a framework to assess antibiotic resistance and virulence risks in pathogens, finding that resistance can increase virulence through genetic changes.

The paper defines a global map of receptor-binding protein compatibility for designing phages targeting Klebsiella and Acinetobacter species.

mulea provides an R package for enrichment analysis across multiple ontologies with empirical FDR correction to address limitations in traditional gene set enrichment methods.

This paper develops a scalable framework for precision phage therapy by combining genomic surveillance and phage typing to target carbapenem-resistant Acinetobacter baumannii.

This study shows chloroplastic ascorbate modulates plant metabolism through global metabolome rewiring and enzyme interactions, independent of oxidative stress.

This study identifies widespread stabilizing selection on metabolite levels in humans, with implications for cardiometabolic health and evolutionary conservation.

This study identifies domain-specific heterochromatin regulators in Schizosaccharomyces pombe using quantitative methods and genetic screening, revealing Dhm2's role in heterochromatin maintenance and replication fidelity.

This study identifies principles of metabolome conservation across species by analyzing multispecies datasets and shows that abundance, essentiality, and disease association predict conservation patterns.

The paper systematically investigates solubility limits of Escherichia coli proteins upon overexpression, revealing that most insoluble proteins aggregate after folding and that high disorder content and low surface stickiness correlate with solubility.

The paper identifies proteins forming phase-separated ribosome-nascent chain complexes and shows they can resume translation after DNA damage.

This study uses a chemical-genetic approach to analyze resistance determinants of E. coli to 15 AMPs, revealing cross-resistance and collateral sensitivity patterns.

This study shows that enzyme promiscuity enables E. coli to adapt to novel substrates through computational modeling and lab evolution experiments.