Kathleen L. Gabrielson

The paper designs an AND-gated CAR T cell receptor called MANTIS that uses extracellular size differences to spatially regulate signaling for precise antigen recognition.

This study evaluates dendrimer-radioconjugates with Actinium-225 and low-dose cisplatin for treating metastatic triple negative breast cancer across different anatomical sites in mice, showing improved survival without long-term toxicity.

This study shows that systemic actinium-225 dendrimer-radioconjugates improve glioblastoma survival in mice, with enhanced efficacy when combined with temozolomide.