Claudio Toma A

This study identifies shared and distinct genetic factors underlying suicidality phenotypes using GWAS and structural equation modelling.

This study performs a transcriptome-wide alternative splicing analysis in bipolar disorder, identifying complex splicing events and candidate genes associated with the disorder.

The MadManic cohort integrates multi-omics and digital phenotyping data from over 4,400 participants to study severe mental disorders and suicidality.

This study identifies sex-specific molecular and functional changes in a schizophrenia model, revealing convergent inhibitory deficits through divergent pathways.

This study uses RNA sequencing in multiplex bipolar disorder families to identify differentially expressed genes and pathways, finding significant lncRNAs and ion homeostasis dysregulation.

This study identifies TAF1-dependent transcriptional dysregulation as a mechanism underlying multiple sclerosis progression and presents an in vivo model for therapeutic development.

This study identifies aberrant CPEB4 splicing and downstream mis-expression of SCZ-risk genes as a novel etiological mechanism in schizophrenia.

The paper examines associations between suicide-related polygenic risk scores and brain structure variability in young people with familial risk of bipolar disorder.

The paper investigates the role of inherited and de novo truncating mutations in high functioning autism and identifies pleiotropic effects of LRP1 variants across psychiatric phenotypes.

This paper analyzes CNTNAP2's role in psychiatric disorders using genomic data and finds it unlikely to be a primary risk gene.

This study identifies rare paternally-inherited structural variants contributing to autism by disrupting noncoding regions and coding genes, with differential parental contributions.