Author

Hongzhi Guan

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0003-3903-5078Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:dimensionality reduction· 1 Assay:metagenomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Bin PengiD· 1 shared Caiyun LiuiD· 1 shared Changhong ReniD· 1 shared Chen‐Rui XiaiD· 1 shared Chunjuan Wang· 1 shared Dong Xu· 1 shared Gaoya Zhou· 1 shared Ge Gao· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Bin PengORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintApr 2, 2026

CNS diseases cerebrospinal fluid single-cell atlas reveals immune characteristics of neuropsychiatric systemic lupus erythematosus

Xing Wang, Shang-Zhu Zhang, Siyuan Fan…·M-T Li

The paper constructs a single-cell atlas of cerebrospinal fluid and blood from CNS diseases, revealing immune features of NPSLE and providing a public resource for future research.

DOI 10.64898/2026.03.31.715151

humanscRNA-seq

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GenomicsbioRxivPreprintJun 10, 2019

Metagenomic Next-generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Central Nervous System Infections: A Multicentre Prospective Study

Siyuan Fan, Xiaojuan Wang, Yafang Hu…·Hongzhi Guan

This study evaluates metagenomic next-generation sequencing (mNGS) of cerebrospinal fluid for diagnosing central nervous system infections, finding it detects pathogens in 36.6% of cases with some false positives and negatives.

2 citations

humanmetagenomics

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