Author

Sarah Inglott

Great Ormond Street HospitalORCID 0000-0003-3917-4254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Jack Luke BartramiD· 2 shared Alice PiapiiD· 1 shared Anastasios KaradimitrisiD· 1 shared Anindita RoyiD· 1 shared Bryan LyeiD· 1 shared Christina HalseyiD· 1 shared Elena PrigmoreiD· 1 shared Eleonora KhabirovaiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Jack Luke BartramORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 22, 2025

Bi-specific CAR-iNKT cell immunotherapy for high-risk KMT2A-rearranged leukemia outperforms CAR-T in an NKG2D-dependent manner and eradicates leptomeningeal disease

Hongwei Ren, Natalina Elliott, Bryan Lye…·Anastasios Karadimitris

This paper develops bi-specific CAR-iNKT cells targeting CD19 and CD133 for KMT2A-rearranged leukemia, showing superior efficacy over CAR-T in eradicating leptomeningeal disease and inducing remission.

2 citations

mouseproteomics

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GenomicsNature MedicinePeer-reviewedMar 14, 2022

Single cell mRNA signals reveal a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia

Eleonora Khabirova, Laura Jardine, Tim H. H. Coorens…·Sam Behjati

The paper identifies a distinct developmental state in KMT2A-rearranged infant B-cell acute lymphoblastic leukemia using single-cell transcriptome analysis.

88 citationstop 1%

humanbulk RNA-seq

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