Rafael Romero-Becerra

This paper develops a domain-adversarial neural network to predict drug combination synergy in leukemia patients using bulk transcriptomics data, showing improved accuracy over existing methods.

This study shows that miR-29 is essential for adult cardiomyocyte function, as its deficiency leads to dilated cardiomyopathy and mitochondrial dysfunction in mice and human cells.

This paper shows that MKK6 deficiency leads to cardiac dysfunction through hyperactivation of the MKK3-p38γ/δ-mTOR pathway, causing hypertrophy and fibrosis, and highlights potential cardiotoxicity of p38 inhibitors.