Sébastien Moretti

StereoMapper clarifies metabolite identity by assigning stereochemically aware relationships, achieving high performance in benchmark datasets and improving GEM accuracy.

The paper examines molecular conservation patterns during molar development in mice and hamsters, finding that conservation varies with developmental stage and is influenced by both intrinsic and extrinsic evolutionary pressures.

The paper identifies an inverse hourglass pattern of conservation in rodent molar development, showing greater conservation at early and late stages than intermediate ones.

The paper examines gene expression variability across organs in three ray-finned fish species, finding that brain-biased genes show stable regulation despite inter-individual differences.

MetaNetX/MNXref provides a unified namespace for metabolites and reactions, improving reconciliation between biochemistry databases and GSMNs with enhanced mapping tools.

Bgee provides an integrated expression atlas and comparative transcriptomics resource for multiple animal species using curated healthy wild-type expression data.

The paper introduces metaboGSE, a method for gene set enrichment analysis using condition-specific metabolic sub-networks, showing higher specificity than GSEA and topGO.

The paper shows taxon sampling unevenly impacts gene tree nodes and introduces a two-step method to construct more reliable model gene trees using SwissTree.