Author

Shea H. Siwik

University of Colorado BoulderORCID 0000-0003-3953-8978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:structural biology· 1

Frequent Co-Authors

Robert BateyiD· 2 shared Aleksandra J. WierzbaiD· 1 shared Amy E. PalmeriD· 1 shared David StelzigiD· 1 shared Lukasz T. OlenginskiiD· 1 shared Shelby R. LennoniD· 1 shared Simone D. HalliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

Robert BateyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 3, 2026

Structure of a dopamine-binding RNA aptamer reveals metal-mediated ligand recognition

Shea H. Siwik, David Stelzig, Simone D. Hall, Robert Batey

The paper reports crystal structures of dopamine-binding RNA aptamers to show how they recognize ligands while maintaining scaffold integrity through metal-mediated interactions and local remodeling.

1 citation

structural biologyexperimental assay

𝕏 PostBluesky

BiochemistryNucleic Acids ResearchPeer-reviewedJun 4, 2025

Structural basis for ring-opening fluorescence by the RhoBAST RNA aptamer.

Shea H. Siwik, Aleksandra J. Wierzba, Shelby R. Lennon…·Robert Batey

The paper determines crystal structures of the RhoBAST RNA aptamer complexed with fluorophores to elucidate the mechanism of ring-opening fluorescence.

5 citations

experimental assayprotein structure prediction

𝕏 PostBluesky