Babu Mathew

This study profiles the metabolome of Ashwagandha to identify bioactive compounds and their associations with therapeutic functions.

The paper identifies Streptococcal Scl1 as a bacterial protein that activates TGFβR1 signaling, driving fibrosis-inflammation in alcohol-associated liver disease through gut microbiota alterations.

The paper identifies PS1145 as a potential therapeutic for reducing systemic inflammation in alcohol-related liver disease by inhibiting IKK phosphorylation and TLR dimerization.

This study identifies elevated chenodeoxycholic acid as a poor prognostic marker in acute liver failure and shows that Bacteroides intestinalis-AM1 reduces bile acids and inflammation, improving liver injury.

This study identifies a mitochondrial quality control mechanism that reverses phagosome maturation arrest caused by Mycobacterium tuberculosis through RAB7 recruitment and lysosomal targeting.