Author

Jennifer Borowsky

QIMR Berghofer Medical Research InstituteORCID 0000-0003-3957-1364Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:diffusion model· 1

Frequent Co-Authors

Barbara LeggettiD· 2 shared Catherine BondiD· 2 shared Cheng LiuiD· 2 shared Diane McKeone· 2 shared Lochlan FennelliD· 2 shared Vicki WhitehalliD· 2 shared Alexandra M. KaneiD· 1 shared Ann‐Marie PatchiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Barbara LeggettORCID

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2 papers

Recent·Most cited

Cancer BiologyBritish Journal of CancerPeer-reviewedFeb 23, 2026

Attenuation of the CpG Island Methylator Phenotype and lack of WNT signaling activation restrains Kras mutant intestinal neoplasia

Lochlan Fennell, Cheng Liu, Alexandra M. Kane…·Vicki Whitehall

This study compares Kras and Braf mutant intestinal neoplasia in mice, showing Kras mutations lead to less aggressive serrated lesions with reduced WNT signaling activation and attenuated DNA methylation changes compared to Braf mutations.

1 citation

mouseDNA methylation

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GenomicsCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2019

Genome Scale Epigenetic Profiling Reveals Five Distinct Subtypes of Colorectal Cancer

Lochlan Fennell, Troy D. Dumenil, Leesa F. Wockner…·Vicki Whitehall

The paper identifies five distinct subtypes of colorectal cancer using DNA methylation profiling and links them to specific mutations and gene body methylation patterns.

54 citationstop 3%

humanDNA methylation

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