BiochemistrybioRxivPreprint
Salt-dependent non-catalytic allostery of human USP14-regulated 26S proteasome
Shitao Zou, Shuwen Zhang, Lihong Zhao, Youdong Mao
This study uses cryo-EM and genetic engineering to show how USP14 non-catalytically regulates proteasome activity through salt-dependent allosteric changes.